Repurposed ALS drug shows promise in mouse model of rare childhood genetic disorder

Journal Reference: Antony Cougnoux, Julia C. Yerger, Mason Fellmeth, Jenny Serra-Vinardell, Fatemeh Navid, Christopher A. Wassif, Niamh X. Cawley, Forbes D. Porter. Reduction of glutamate neurotoxicity: A novel therapeutic approach for Niemann-Pick disease, type C1. Molecular Genetics and Metabolism, 2021; DOI: 10.1016/j.ymgme.2021.11.008 The study was conducted by Forbes D. Porter, M.D., Ph.D., of NIH’s Eunice … Read more

Lucid Air Dream Edition Range vs Tesla Model S Plaid and Others: Real Fast Charge Speed ​​Comparison | Gadgets News

Our colleagues from InsideEVs shared measurements of fast charging of the Lucid Air Dream Edition R – the electric car with the largest, for today, the power reserve on one charge. Previously, they tested several other models in a similar way, including the Tesla Model S Plaid – here are their results: Lucid Air Dream … Read more

In Reggio, basketball is female: “I dream of the Scudetto model Venice”

Veronica Bartoli, the president-owner on the future: “You win with the continuity of the group” In Reggio Emilia, basketball is a woman. First with Licia Ferrarini, president until 2020, now with Veronica Bartoli, who took over from Ferrarini and from September 2021 also became the majority shareholder of Pallacanestro Reggiana with 81% of shares. Now … Read more

Presidential election in Chile: the country chooses its model in an unprecedented ballot

Support for the far-right Chilean presidential candidate José Antonio Kast at the campaign’s closing rally in Santiago on November 18, 2021. ERNESTO BENAVIDES / AFP In the golden light of the sunset on the outskirts of Santiago, supporters of José Antonio Kast wave the Chilean star flag – very present at the end-of-campaign meeting of … Read more

“We, business leaders, support the proposed revision of the European directive on the publication of extra-financial information, a new stage in the evolution of our economic model”

Tribune. If the new version of the European Directive on the communication of sustainability data (Corporate Sustainability Reporting Directive, or CSRD) was to be adopted by European legislators, it would require more than 50,000 large companies and listed companies in the European Union (EU) to publish information about their supply chain, their impacts on ecosystems, … Read more

Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer’s disease

Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer’s disease – NovLink Home Mash I Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer’s disease We would like to thank the author of this article for this outstanding content Restoring normal sleep reduces amyloid-beta accumulation in mouse model of Alzheimer’s disease

Food safety model may help pandemic management

Journal Reference: Julie Henderson, Paul R. Ward, Emma Tonkin, Samantha B. Meyer, Heath Pillen, Dean McCullum, Barbara Toson, Trevor Webb, John Coveney, Annabelle Wilson. Developing and Maintaining Public Trust During and Post-COVID-19: Can We Apply a Model Developed for Responding to Food Scares? Frontiers in Public Health, 2020; 8 DOI: 10.3389/fpubh.2020.00369 “It’s crucial that the … Read more

A mathematical model to help optimize vaccine development

Journal Reference: Gennady Bocharov, Dmitry Grebennikov, Jordi Argilaguet, Andreas Meyerhans. Examining the cooperativity mode of antibody and CD8 T cell immune responses for vaccinology. Trends in Immunology, 2021; 42 (10): 852 DOI: 10.1016/j.it.2021.08.003 In a recent Forum article in Trends in Immunology a group of researchers at UPF and the Marchuk Institute of Numerical Mathematics … Read more

Scientists show how light therapy treats depression in mice model

Journal Reference: Iwona Olejniczak, Jürgen A. Ripperger, Federica Sandrelli, Anna Schnell, Laureen Mansencal-Strittmatter, Katrin Wendrich, Ka Yi Hui, Andrea Brenna, Naila Ben Fredj, Urs Albrecht. Light affects behavioral despair involving the clock gene Period 1. PLOS Genetics, 2021; 17 (7): e1009625 DOI: 10.1371/journal.pgen.1009625 Nighttime light has strong effects on the physiology and behavior of mammals. … Read more

A new Earth bombardment model

Journal Reference: Marchi, S., Drabon, N., Schulz, T. et al. Delayed and variable late Archaean atmospheric oxidation due to high collision rates on Earth. Nat. Geosci, 2021 DOI: 10.1038/s41561-021-00835-9 When large asteroids or comets struck early Earth, the energy released melted and vaporized rocky materials in the Earth’s crust. The small droplets of molten rock … Read more